The main theme of the PCI-DSS 3.2.1 standard is security. The hub-spoke topology is a natural choice for setting up a regulated environment. It's easier to create an infrastructure that allows secure communications. Network controls are placed in both hub-spoke networks and follow the Microsoft zero-trust model. The controls can be tuned with least-privilege to secure traffic, giving access on a need-to-know basis. In addition, you can apply several defense-in-depth approaches by adding controls at each network hop.