When you select a database to store operational data, it is crucial to consider how the data should be structured, which queries it will answer, how fast it will provide answers, and the resiliency of the data platform itself. In addition to these general considerations are software as a service (SaaS) implications for operational data, such as performance isolation, tenant security, and unique characteristics and design patterns that are typical of data for multi-tenant SaaS applications. This guide discusses how these factors apply to using a PostgreSQL database on Amazon Web Services (AWS) as the primary operational data store for a multi-tenant SaaS application. Specifically, the guide focuses on two AWS managed PostgreSQL options: Amazon Aurora PostgreSQL-Compatible Edition and Amazon Relational Database Service (Amazon RDS) for PostgreSQL.